Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sphingosine 1-phosphate (S1P) activates MCs and induces antimicrobial peptide (AMP) production of both LCN2 and Cathelicidin AMP (CAMP). hMCs and mMCs were stimulated with PBS (control) or 200 nM S1P for 4 (for q-PCR) or 24 (for ELISA) hr. (a) Human LCN2 and (b) CAMP expression measured by q-PCR. LCN2 secretion from (c) hMCs or (d) mMCs quantified by ELISA. (e) CAMP protein secretion from hMCs quantified by ELISA. *: p < 0.05, ****: p < 0.0001.
