Figure 5.

Scheme illustrating the plausible effects of fatty acids extracted from chronic kidney disease (CKD) patients’ serum on the expression of genes associated with lipid synthesis and release in hepatocyte. ACC—acetyl-coenzyme A carboxylase, FASNfatty acid synthase, SCD1—stearoyl-CoA desaturase, ELOVL6—fatty acid elongase 6, DGAT1—diacylglycerol O-acyltransferase 1, MTTP—microsomal triglyceride transfer protein, ApoB—apolipoprotein B, DAG—diacylglycerol, TAG—triacylglycerol, VLDL—very low density lipoprotein.