Table 2.

The percent content of the main classes of fatty acids in serum of patients at successive stages of chronic kidney disease (CKD). The data are presented as fatty acid proportions (%). * statistically significant comparing to controls at p < 0.05; # p < 0.01. SFA—saturated fatty acids, MUFA—monounsaturated fatty acids, PUFA—polyunsaturated fatty acids.

Item	Healthy Control	CKD 1-2	CKD 3a	CKD 3b	CKD 4-5	HD	PD	Tx
14:0	1.18 ± 0.06	1.18 ± 0.06	1.26 ± 0.07	1.18 ± 0.08	1.06 ± 0.06	1.17 ± 0.08	0.98 ± 0.06 *	1.33 ± 0.12
16:0	23.00 ± 0.33	23.04 ±0.30	23.64 ± 0.50	23.21 ± 0.30	23.50 ± 0.39	23.51 ± 0.39	22.79 ± 0.37	23.86 ± 0.45
18:0	7.23 ± 0.12	7.15 ± 0.09	7.12 ± 0.16	7.02 ± 0.16	6.79 ± 0.18 *	7.04 ± 0.20	6.87 ± 0.18	6.72 ± 0.13 #
Other SFA	1.57 ± 0.04	2.08 ± 0.09 #	1.91 ± 0.11 #	1.98 ± 0.11 #	2.00 ± 0.11 #	2.04 ± 0.10 #	1.48 ± 0.07	2.27 ± 0.10 #
Total SFA	32.97 ± 0.34	33.44 ± 0.36	33.93 ± 0.14	33.38 ± 0.44	33.36 ± 0.49	33.75 ± 0.38	32.12 ± 0.51	34.18 ± 0.57
14:1	0.07 ± 0.01	0.07 ± 0.01	0.08 ± 0.01	0.07 ± 0.01	0.06 ± 0.01	0.07 ± 0.01	0.05 ± 0.00 #	0.08 ± 0.01
16:1	1.93 ± 0.30	2.80 ± 0.17 #	2.41 ± 0.32	2.85 ± 0.17 #	2.22 ± 0.35	2.78 ± 0.22 *	2.76 ± 0.15 *	3.06 ± 0.17 #
18:1	26.04 ± 0.55	26.04 ± 0.47	25.68 ± 1.29	27.56 ± 0.59	28.57 ± 0.49 #	29.24 ± 0.75 #	29.81 ± 0.58 #	28.00 ± 0.64 *
Other MUFA	0.47 ± 0.02	0.46 ± 0.01	0.47 ± 0.02	0.51 ± 0.02	0.57 ± 0.07	0.53 ± 0.02	0.47 ± 0.02	0.53 ± 0.03
Total MUFA	29.60 ± 0.64	29.59 ± 0.54	30.39 ± 0.65	31.09 ± 0.62	32.19 ± 0.54 #	32.81 ± 0.87 #	33.10 ± 0.68 #	31.67 ± 0.73 *
18:3n-3	0.35 ± 0.02	0.30 ± 0.02	0.29 ± 0.03	0.27 ± 0.02 #	0.24 ± 0.03 #	0.20 ± 0.02 #	0.24 ± 0.02 #	0.21 ± 0.02 #
20:5n-3	1.11 ± 0.13	0.85 ± 0.07	0.81 ± 0.07	0.77 ± 0.07 *	0.77 ± 0.11	0.72 ± 0.07 *	0.95 ± 0.05	0.60 ± 0.06 #
22:6n-3	1.14 ± 0.08	1.01 ± 0.06	1.03 ± 0.08	1.06 ± 0.06	0.96 ± 0.10	0.92 ± 0.09	1.38 ± 0.08 *	0.88 ± 0.08 *
Other n-3 PUFA	0.39 ± 0.00	0.36 ± 0.01	0.34 ± 0.02 *	0.37 ± 0.02	0.34 ± 0.01 #	0.36 ± 0.01	0.50 ± 0.02 #	0.32 ± 0.02 #
Total n-3 PUFA	2.99 ± 0.21	2.52 ± 0.13	2.47 ± 0.15	2.48 ± 0.13	2.31 ± 0.20 *	2.19 ± 0.16 #	3.08 ± 0.13	2.01 ± 0.13 #
18:2n-6	24.90 ± 0.64	25.14 ± 0.60	24.31 ± 0.99	23.85 ± 0.76	23.99 ± 0.95	22.25 ± 0.64 #	22.73 ± 0.67 *	24.13 ± 0.82
20:4n-6	5.56 ± 0.20	5.05 ± 0.17	4.93 ± 0.22 *	5.11 ± 0.17	4.66 ± 0.27 #	4.93 ± 0.25	5.15 ± 0.20	4.03 ± 0.17 #
Other n-6 PUFA	1.44 ± 0.04	1.37 ± 0.04	1.30 ± 0.04 *	1.23 ± 0.05 #	1.10 ± 0.07 #	1.13 ± 0.06 #	1.43 ± 0.04	1.12 ± 0.04 #
Total n-6 PUFA	31.90 ± 0.67	31.57 ± 0.67	30.54 ± 0.24	30.19 ± 0.77	29.72 ± 0.90	28.31 ± 0.72 #	29.31 ± 0.77 *	29.28 ± 0.91 *