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Effects of linagliptin (10 mg/kg BW/day) on (A) body weight, (B) fasting blood glucose (FBG), (C) total cholesterol, and (D) glucagon-like peptide-1 (GLP-1) in PS19 mice being fed a low-fat diet (LFD) or high-fat diet (HFD) for approximately 6 months. Mean ± SD. One-way ANOVA, followed by Bonferroni post hoc tests was used. Significant differences are indicated when * p < 0.05, ** p < 0.01, or *** p < 0.001.
