| ALS | amyotrophic lateral sclerosis |
| ALSFRS-R | revised ALS functional rating scale |
| ANG | angiogenin |
| ANOVA | analysis of variance |
| ATXN2 | ataxin 2 |
| C9orf72 | chromosome 9 open reading frame 72 |
| CCNF | G2/mitotic-specific cyclin F |
| CHCHD10 | coiled-coil-helix-coiled-coil-helix domain containing 10 |
| CHMP2B | charged multivesicular body protein 2B |
| DAO | D-amino acid oxidase |
| DCTN1 | dynactin-1 |
| DNA | deoxyribonucleic acid |
| EDDs | electron dense deposits |
| ELP3 | elongator complex protein 3 |
| ERBB4 | transmembrane tyrosine kinase receptor |
| EWSR1 | Ewing sarcoma break point region 1 |
| FIG4 | phosphoinositide 5 phosphatase |
| FUS | fused in sarcoma |
| GATK | genome analysis tool kit |
| GFAP | glial fibrillary acidic protein |
| GLE1 | nucleoporin GLE 1 protein |
| GRN | granulin |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 |
| IBA-1 | ionized calcium-binding adapter molecule 1 |
| IgG | immunoglobulin G |
| ip | intraperitoneal |
| MATR3 | Matrin 3 |
| MCP-1 | macrophage chemoattractant protein 1 |
| NEFH | neurofilament heavy |
| NEK1 | never in mitosis gene a related kinase 1 |
| NGS | next generation sequencing |
| OPTN | optineurin |
| PBS | phosphate buffered saline |
| PFN1 | profilin 1 |
| s.e.m. | standard error of means |
| s.d. | standard deviation |
| SETX | senataxin |
| SIGMAR1 | sigma-non-opioid intracellular receptor 1 |
| SOD1 | superoxide dismutase 1 |
| SPG11 | spataxin 11 |
| SQSTM1 | sequestosome 1 |
| SS18L1 | NBAF chromatin remodeling complex subunit |
| TAF15 | TATA-Box binding protein associated Factor 15 |
| TARDBP | transactive response DNA-binding protein |
| TBK1 | TANK binding kinase 1 / NF-Kappa-B-activating kinase |
| TNF-α | tumor necrosis factor alpha |
| TUBA4A | tubulin α 4A |
| UBQLN2 | ubiquilin 2 |
| UPS | ubiquitin-proteasome system |
| VAPB | vesicle-associated membrane protein |
| VCP | valosin containing protein |