Table 3.
The changes of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30) scores between groups.
| Variable | ONS Group (n = 15) | Non-ONS Group (n = 19) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0w | 8w | Δ | p a | 0w | 8w | Δ | p b | p c | p d | |
| Global health status/QoL | ||||||||||
| 55.6 ± 4.58 | 65.6 ± 4.06 | 10 ± 5.16 | 0.065 | 54.4 ± 4.66 | 59.2 ± 4.97 | 4.83 ± 4.29 | 0.323 | 0.929 | 0.477 | |
| Functional scales | ||||||||||
| Physical | 76.4 ± 4.06 | 83.6 ± 2.67 | 7.11 ± 4.34 | 0.154 | 75.8 ± 4.71 | 74.4 ± 3.92 | −1.4 ± 3.55 | 0.825 | 0.847 | 0.306 |
| Role | 85.6 ± 5.11 | 92.2 ± 3.59 | 6.67 ± 6.67 | 0.286 | 82.5 ± 4.85 | 71.9 ± 6.25 | −10.5 ± 7.45 | 0.171 | 0.699 | 0.158 |
| Emotional | 89.4 ± 2.75 | 88.9 ± 5.06 | −0.56 ± 3.86 | 0.932 | 85.5 ± 4.12 | 81.6 ± 4.06 | −3.95 ± 4.05 | 0.507 | 0.885 | 0.604 |
| Cognitive | 93.3 ± 2.72 | 91.1 ± 2.22 | −2.22 ± 2.75 | 0.222 | 80.7 ± 4.28 | 81.6 ± 3.58 | 0.88 ± 4.32 | 0.906 | 0.026 | 0.677 |
| Social | 85.6 ± 4.26 | 88.9 ± 3.87 | 3.33 ± 4.93 | 0.603 | 91.2 ± 3.46 | 89.5 ± 5.13 | −1.76 ± 4.75 | 0.461 | 0.215 | 0.306 |
| Symptom scales | ||||||||||
| Fatigue | 37 ± 4.93 | 20.7 ± 4.58 | −16.3 ± 7.1 | 0.041 | 33.3 ± 5.17 | 36.3 ± 5.69 | 2.93 ± 5.88 | 0.616 | 0.467 | 0.064 |
| Nausea/Vomiting | 8.9 ± 3.59 | 7.78 ± 3.2 | −1.11 ± 4.14 | 0.705 | 13.2 ± 4.15 | 9.6 ± 3.45 | −3.51 ± 3.01 | 0.221 | 0.480 | 0.512 |
| Pain | 4.45 ± 1.97 | 2.22 ± 1.51 | −2.22 ± 2.22 | 0.317 | 26.3 ± 6.66 | 14.9 ± 4.92 | −11.4 ± 5.71 | 0.039 | 0.006 | 0.178 |
| Dyspnea | 4.44 ± 3.03 | 11.1 ± 5.31 | 6.67 ± 3.56 | 0.102 | 15.8 ± 3.92 | 15.8 ± 4.68 | 0 ± 4.41 | 0.739 | 0.038 | 0.283 |
| Insomnia | 26.7 ± 7.42 | 26.7 ± 8.1 | 0 ± 9.2 | 0.722 | 24.6 ± 5 | 24.6 ± 7.14 | 0 ± 6.24 | 0.672 | 0.940 | 0.615 |
| Anorexia | 33.3 ± 5.63 | 17.8 ± 7.88 | −15.6 ± 8.52 | 0.112 | 29.8 ± 7.16 | 24.6 ± 6.16 | −5.26 ± 7.33 | 0.856 | 0.423 | 0.248 |
| Constipation | 11.1 ± 5.31 | 11.1 ± 4.2 | 0 ± 6.51 | 1.000 | 19.3 ± 6.41 | 12.3 ± 4.57 | −7.02 ± 7.89 | 0.359 | 0.355 | 0.359 |
| Diarrhea | 4.44 ± 3.03 | 2.22 ± 2.22 | −2.22 ± 3.94 | 0.564 | 12.3 ± 5.23 | 10.5 ± 5.13 | −1.75 ± 4.01 | 0.655 | 0.313 | 0.944 |
| Financial difficulties | 33.3 ± 5.63 | 22.2 ± 5.31 | −11.1 ± 7.03 | 0.154 | 35.1 ± 6.97 | 33.3 ± 5.7 | −1.75 ± 6.97 | 0.668 | 0.955 | 0.284 |
Values are nean ± SE. Change (Δ) = (8-week data) − (0-week data). pa values were derived from the Wilcoxon signed rank test between 0 weeks (baseline) and 8 weeks in the ONS group. pb values were derived from the Wilcoxon signed rank test between 0 weeks (baseline) and 8 weeks in the non-ONS group. pc values were derived from the Mann–Whitney test between the 0-week values of the two groups. pd values were derived from the Mann–Whitney test between the change values (Δ) of the two groups.