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. 2019 May 27;20(10):2601. doi: 10.3390/ijms20102601

Figure 3.

Figure 3

Localization and relative amount of TFAM-bound mtDNA at three mtDNA regions in liver from 28- and 32-month-old rats. (A) The amplified products enclose part of D-loop, Ori-L, and DR1-harboring regions, as depicted in the rat mtDNA map. (B) Bars represent the mean and SEM of the relative amounts of TFAM-bound mtDNA of two independent experiments performed in triplicate. Number of analyzed animals: 5 in the 28-month-old group, 4 in the 32-month-old group; * p < 0.05, Mann Whitney test. Bars not showing the same superscript differ significantly; p < 0.01, Dunn’s Multiple comparison test after Kruskal-Wallis test.