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. 2019 Apr 27;11(5):968. doi: 10.3390/nu11050968

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Evaluation of morphological changes and enterocyte vacuolization in the distal ileum of preterm lambs by H&E staining in control (A), UP-exposed (B), UP + carrier-exposed (C), and UP + sterol + carrier-exposed fetal lambs (D). Injury of the villi tips (arrows) was observed after 6 d UP exposure, which was prevented by carrier and/or sterol + carrier treatment. The size of the vacuoles within the enterocytes was increased in all experimental groups and most profoundly in UP + carrier and UP + sterol + carrier animals. Scale bar indicates 200 µm. Abbreviations: H&E, hematoxylin and eosin; UP, U. parvum.