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. 2019 May 20;20(10):2480. doi: 10.3390/ijms20102480

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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JMV-2959-treated mice experience a similar amount of Phase IV seizures. (A) Correlation between number of Phase III and IV seizures visually observed and number of hippocampal discharges on EEG (controls and JMV-2959-treated mice taken together; n = 10 pairs). Pearson correlation (p < 0.001; Pearson’s r = 0.9144). (B) Twenty-nine percent of JMV-2959-treated mice (n = 7) experienced Phase IV seizures and 38% of saline-treated controls (n = 8) did. Fisher’s exact test (p > 0.05). EEG, electro-encephalography.