Table 1.

Effect of unilateral nephrectomy on biochemical parameters in 127 healthy kidney donors. Study design and methods are described previously [51,52].

Variable	N	Before Donation	After Donation	Absolute Difference	Change in Mean (%)	p-Value
Urinary homoarginine excretion (µmol/24 h)	127	4.0 ± 4.4	3.0 ± 2.3	1.1 ± 3.4	−25	0.001
Urinary urea excretion (mmol/24 h)	125	420 ± 127	394 ± 111	26 ± 140	−6	0.04
Urinary sodium excretion (mmol/24 h)	125	203 ± 72	176 ± 65	27 ± 82	−13	<0.001
Plasma homoarginine (µmol/L)	125	1.7 ± 0.6	1.5 ± 0.5	0.2 ± 0.4	−12	<0.001
Plasma guanidinoacetate (µmol/L)	127	2.9 ± 1.1	2.3 ± 0.5	0.6 ± 1.0	−23	<0.001
Serum creatinine (µmol/L)	127	73 ± 12	107 ± 21	−35 ± 11	+47	<0.001
mGFR (mL/min)	127	118 ± 24	74 ± 14	43 ± 14	−37	<0.001
eGFR (mL/min/1.73 m2)	127	95 ± 16	60 ± 12	34 ± 10	−37	<0.001

Abbreviations: eGFR: estimated glomerular filtration rate. mGFR: measured glomerular filtration rate.