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. 2019 May 20;20(10):2492. doi: 10.3390/ijms20102492

Table 12.

Effect of PHPs and PCPs on MDA production in different microalgae.

PHRs/PCPs Concentration in Medium * (mg/L) Strain Maximal MDA Increase ** Ref.
Amoxicillin 20 Microcystis aeruginosa 1.18-fold [219]
Amoxicillin 0.001 Microcystis aeruginosa ~2.6-fold [220]
Amoxicillin 0.0005 Microcystis aeruginosa ~1.7-fold [221]
Amoxicillin 0.0005 Microcystis aeruginosa ~1.5-fold [211]
Ciprofloxacin 100 Chlamydomonas mexicana ~4-fold [108]
Ciprofloxacin 2.5 Pseudokirchneriella subcapitata ~2.2-fold [222]
Enrofloxacin 100 Chlamydomonas mexicana ~1.8-fold [95]
Micractinium resseri ~9.3-fold
Enrofloxacin 80 Scenedesmus obliquus 2.4-fold [97]
Norfloxacin 20 Microcystis aeruginosa 1.48-fold [219]
Norfloxacin 60 Scenedesmus obliquus 1.86-fold [99]
Levofloxacin 0.1 Microcystis flosaquae 3.84-fold [102]
Tetracycline 0.5 Microcystis aeruginosa 1.75-fold [57]
5 Selenastrum capricornutum ~6-fold
Doxycycline 5 Microcystis aeruginosa 1.8-fold [71]
Chlortetracycline 60 Chlorella pyrenoidosa 2.5-fold [64]
48 Microcystis aeruginosa 2.7-fold
Florfenicol 0.025 Microcystis flosaquae 2.06-fold [46]
Florfenicol 46 → 160 Chlorella sp. 25.6-fold F [52]
Thiamphenicol 0.07 Microcystis flosaquae ~2.3-fold [46]
Erythromycin 0.03 Microcystis flosaquae ~5-fold [113]
Erythromycin 0.3 Pseudokirchneriella subcapitata ~3.2-fold [222]
Spiramycin 0.001 Microcystis aeruginosa ~3.2-fold [220]
Sulfamethoxazole 2.5 Pseudokirchneriella subcapitata ~1.9-fold [222]
Carbamazepine 200 Dunaliella tertiolecta ~9-fold [170]
Ethinylestradiol 0.001 Dunaliella salina ~2.37-fold [179]
Triclosan 0.405 Chlamydomonas reinhardtii 1.33-fold [194]
Triclosan 4 Chlamydomonas reinhardtii ~6.5-fold [195]

*: PHRs/PCPs concentration corresponding to the maximal uplift of MDA; **: in comparison to the control (no PHRs/PCPs); F: in comparison to florfenicol at 46 mg/L; →: increase in concentration.