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The effects of SI-4650 on cell apoptosis and the expression levels of Bcl-2 and Bax. (A) Flow cytometry of A549 cells treated with DMSO (A) or SI-4650 (B) at 80 µM for 48 h and stained with a mixture of FITC-annexin V and PI. (C) Protein expression levels were measured by Western blot analysis. The A549 cells were treated with SI-4650 at 80 µM for 48 h, and β-actin was used as the internal control. (D) The relative ratio of Bax and Bcl-2. *p < 0.05.
