A Venn diagram of genes shared between different autosomal dominant IRD forms. Genes that cause RP are indicated in the yellow circle, genes that cause macular dystrophies are indicated in the blue circle, and genes that cause cone-rod dystrophies are indicated in the red circle. The genes CRX and SEMA4A cause both RP and cone-rod dystrophy, whereas the genes BEST1, FSCN2 and GUCA1B cause both RP and cone-rod dystrophy. PRPH2 is associated with all three forms. PROM1 causes both autosomal dominant macula dystrophy and cone-rod dystrophy but not adRP. The genes indicated in blue (IMPDH1, CRX and OTX2) also cause autosomal dominant LCA.