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. 2019 May 17;20(10):2456. doi: 10.3390/ijms20102456

Figure 1.

Figure 1

MOTS-c administration increases the ability of cold adaptation upon acute cold exposure. (A) Experimental design for the study in MOTS-c administration upon cold exposure. (B) The serum level of MOTS-c following 4 °C exposure and the standard curve and 450 nm absorption signaling are shown (n = 8 per group). (C,D) Body temperature during cold exposure and the change in body temperature was analyzed at the first and sixth days of cold exposure. (n = 8 per group). (E,F) Body weight during cold exposure and the change in body weight was analyzed at the first and sixth days of cold exposure (n = 8 per group). (G,H) Food intake during cold exposure and the change in food intake was analyzed at the first and sixth days of cold exposure. (n = 8 per group). (I,J) The serum levels of triglycerides and glucose were detected at the first and sixth days of cold exposure. (n = 8 per group). All data are represented as mean ± SEM. Differences between the two groups were determined by a two-tailed Student’s t-test. * p < 0.05, n.s. = not significant.