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. 2019 Jun 6;41(1):481–488. doi: 10.1080/0886022X.2019.1621759

Figure 1.

Figure 1.

UUO caused obvious renal interstitial fibrosis. Pathological changes in the kidney at 0, 7, and 14 days after the UUO operation (A) HE staining (scale bar = 50−µm). (B) Masson staining (scale bar = 50 µm). (C) The relative gene expression of COL1A1, α-SMA and fibronectin in the kidney at 0, 7, and 14 days after the UUO operation. (D) Relative normalized gene expression of DDR2 in the kidney, evaluated by real-time qPCR at 0, 7, and 14 days after the UUO operation. (E) The hydroxyproline content in the kidney at 0, 7, and 14 days after the UUO operation (****p < .0001). (F) Western blot analysis of the protein level of α-SMA at 0, 7, 14, and 21 days after the UUO operation.