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. 2019 Jun 6;41(1):481–488. doi: 10.1080/0886022X.2019.1621759

Figure 3.

Figure 3.

Calcium dobesilate affected the expression of DDR2 in the renal tissue of UUO mice, reduced renal interstitial fibrosis, and protected the renal function. Pathological changes in the kidney at 14 days after the UUO operation. (A) HE staining (scale bar = 50 µm). (B) Masson staining (scale bar = 50 µm). (C) The relative expression of the fibrosis related gene α-SMA in the kidney at 14 days after the UUO operation (*p < .05). (D) The relative gene expression of DDR2 in the kidney at 14 days after the UUO operation (*p < .05, **p < .005). (E) The relative expression of the renoprotective gene HO-1 in the kidney at 14 days after the UUO operation (**p < .005, ****p < .0001).