Figure 1.
Effects of the leaf extract of E. senticosus on object recognition memory in mice. (A) The leaf extract of E. senticosus (500 mg/kg, p.o.) (ESL) or vehicle solution (Veh) was administered for 17 days to mice (males, 8 weeks old). On administration day 14, an object recognition test was started. (B) The preference indices of the training and test sessions are shown. Above 50% of the preferential index in a test session shows memory enhancement. (*** P < 0.001, repeated measures two-way ANOVA, post hoc Bonferroni test; n = 5 mice). (C) Locomotion was evaluated as moved distances for 10 min in an open field box on day14. Statistical analysis was done by one-way ANOVA. P > 0.05. (D) Body weights in two groups were measured and analyzed by repeated measures two-way ANOVA. P > 0.05.