Table 2.
Hazard ratios (95%CI) for risk of type 2 diabetes according to waist circumference group by trajectory analysis, N = 4, 992
| No. of Persons | No. of T2DM incidences | Person years, follow-up | Age adjusted rate | Model 1a | Model 2b | Model 3c | |
|---|---|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
| WC Group A | 635 | 9 | 4033.6 | 193.9 | 1.0 | 1.0 | 1.0 |
| WC Group B | 1426 | 52 | 8984.2 | 498.4 | 2.6 (1.3–5.2) | 2.5 (1.2–5.0) | 2.2 (1.1–4.6) |
| WC Group C | 1662 | 75 | 10,392.1 | 661.9 | 3.2 (1.6–6.4) | 3.0 (1.5–5.9) | 2.5 (1.2–5.0) |
| WC Group D | 1012 | 104 | 6158.6 | 1845.9 | 7.4 (3.7–14.8) | 7.0 (3.5–13.8) | 5.4 (2.7–10.9) |
| WC Group E | 257 | 36 | 1549.2 | 2045.0 | 10.0 (4.8–20.7) | 10.0 (4.8–20.8) | 7.3 (3.5–15.4) |
| P for trend | <.0001 | <.0001 | <.0001 | ||||
| C statistic | 0.6841 | 0.6956 | 0.8689 |
Abbreviation: T2DM type 2 diabetes mellitus, WC waist circumference, HR hazard ratio, CI confidence interval
aModel 1: Adjusted for age, age square, sex, and family history of type 2 diabetes mellitus at wave 4
bModel 2: Adjusted for Model 2 + smoking status, alcohol intake, physical exercise, and body mass index at wave 4
cModel 3: Adjusted for Model 3 + systolic blood pressure, and total cholesterol at wave 4