Table 1.

Recommendations Extraction (NICE guideline as an example)

Basic information
Title of guideline		Diabetes in pregnancy: Management of diabetes and its complications from preconception to the postnatal period
Development institute		NICE
Publication year		Published 2008, updated 2015
Guideline type		Evidence-based guideline
Guideline methodology		Developed in accordance with the NICE guideline development process
Quality assessment of evidence and grading of strength of recommendations		GRADE system
Guideline Currency	Literature search date	2014.6
	Search strategy	A comprehensive literature search was performed
Methodological quality of guideline
AGREE II scores	Domain 1. Scope and Purpose	100%
	Domain 2. Stakeholder Involvement	100%
	Domain 3. Rigor of Development	100%
	Domain 4. Clarity of Presentation	100%
	Domain 5. Applicability	100%
	Domain 6. Editorial Independence	100%
	Overall assessment	☑Recommend ☐Recommend with modifications ☐Would not recommend
Recommendation extraction and assessment
Health questions		What are the target ranges for blood glucose in women with gestational diabetes during pregnancy?
Specific recommendation		Advice pregnant women with any form of diabetes to maintain their capillary plasma glucose below the following target levels, if these are achievable without causing problematic hypoglycaemia: 1) fasting: 5.3 mmol/L(#1) and 2) 1 h after meals: 7.8 mmol/L(#2) or 3) 2 h after meals: 6.4 mmol/L.(#3)
Strength of recommendation		☑Strong ☐Week
Supporting evidence		(#1) 1 secondary analysis of RCT data, 1 RCT, very low (#2) 1 retrospective cohort study, very low (#3) 1 secondary analysis of RCT data, very low
Consistency appraisal		Search strategy and selection of evidence ☐1 ☐2 ☐3 ☐4 ☐5 ☐6 ☑7
		Evidence and interpretation ☐1 ☐2 ☐3 ☐4 ☐5 ☐6 ☑7
		Interpretation and recommendation ☐1 ☐2 ☐3 ☐4 ☐5 ☐6 ☑7