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. 2019 Jun 13;18:109. doi: 10.1186/s12934-019-1156-3

Fig. 4.

Fig. 4

The set of five reactions, panels ae, belonging to Category 3 (C3). C3 reactions and derivatives are neither present in iML1515 nor associated with E. coli in KEGG and EcoCyc. However, according to KEGG, the reactions occur in other organisms. Each of the five panels is divided into three sections (I) the balanced reaction developed by our workflow indicating the reactants, products, and the promiscuous enzyme, (II) the RDM pattern showing the Reaction Center (R) in red, and (III) the native reaction catalyzed by the potentially promiscuous enzyme, as catalogued in KEGG