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. 2019 Jun 13;18:109. doi: 10.1186/s12934-019-1156-3

Fig. 6.

Fig. 6

Main steps of EMMA workflow customized to extend the E. coli iML1515 model with predicted reactions. Step 1: predict promiscuous transformations and derivatives using PROXIMAL. Step 2: compare derivatives with measured metabolic dataset(s). Step 3: curation and stoichiometric balancing of reactions