Table 1.
List of C1 reactions predicted by EMMA and their parallel reactions in E. coli iML1515
| EC number (gene) | Reaction | |
|---|---|---|
|
Predicted iML1515 |
2.4.2.10 (b3642) 3.2.2.10 (b2795) |
Cytosine + 5-phospho-α-d-ribose-1-diphosphate ⇋ CMP + diphosphate Cytosine + d-ribose-5-phosphate ⇋ CMP + H2O |
|
Predicted iML1515 |
1.1.1.79 (b1033) 1.1.1.95 (b2913) |
2-Oxoglutarate + NADPH + H+ ⇋ 2-hydroxyglutarate + NADP+ 2-Oxoglutarate + NADH + H+ ⇋ 2-hydroxyglutarate + NAD+ |
|
Predicted KEGG |
3.6.1.7 (b0968) 6.3.5.5 (b0032 or b0033) |
Bicarbonate + orthophosphate ⇋ carboxyphosphate + H2O Bicarbonate + ATP ⇋ carboxyphosphate + ADP |
|
Predicted iML1515 |
2.8.3.10 (b0615) 2.8.3.8 (b2221 and b2222 or b1694) or 2.8.3.9 (b2221 and b2222) |
Acetoacetyl-CoA + citrate ⇋ acetoacetate + (3S)-citryl-CoA Acetoacetyl-CoA + acetate ⇋ acetoacetate + acetyl-CoA |
Each of the predicted/iML1515 reaction pair occurs between the same substrate and product but utilize different co-substrate or cofactors