Fig. 6.

Increased secretion of chemokines and cytokines in CM of PANC-1 TS co-cultured with PSCs. a Representative images of human cytokine array analysis in CM of PANC-1 TS under mono-culture and PSC co-culture conditions. Two factors were detected only in co-culture CMs (yellow boxes); five showed over 5-fold increase under co-culture conditions (red boxes). In the graph are the factors showing increase by more than 2-folds. b Upregulation of the TGF-β1 and EMT-related cytokines in CM under TS-PSC co-culture conditions. CM: conditioned media; POS: positive control; NEG: negative control