Fig. 1.
a Difference of ΔBASDAI between responders and poor-responders. ΔBASDAI = (BASDAIweek0 – BASDAIweek12)/BASDAIweek0. b The difference of IgG-Gal ratio between responders and poor-responders before treatment. c IgG-Gal ratio variance of responders and poor-responders during treatment. d ΔIgG-Gal ratio variance of responders and poor-responders during treatment. The blank dots and black lines in C and D represent the mean value and standard error (se) interval respectively. e ROC curve of different indicators predicting patient response to etanercept. f Comparison between different models of patient response prediction. LG: logistic regression, RF: randomforest, SVM: support vector machine, NB: naviebayes, NN: neural network, LDA: linear discriminant analysis, MDA: mixture discriminant analysis, FDA: flexible discriminant analysis