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. 2019 May 2;244(9):743–751. doi: 10.1177/1535370219846497

Figure 1.

Figure 1.

BBB disruption in the LPS100 + HT group. (a) Schematic representation of the treatment protocol. Epi-fluorescence microscopy images of FITC labeling in the cingulate cortex indicating the control (b), HT (c), LPS100 (d), and LPS100 + HT (e) groups. (f) The proportion of the FITC-positive cortical area is compared among the experimental groups. The proportion of the FITC-positive cortical area significantly increased in the LPS100 + HT group compared with that in the control group. n = 3 in each group, *: p < 0.05, one-way analysis of variance followed by Tukey’s multiple comparison test. Scale bar: 300 µm. FITC: fluorescein isothiocyanate; HT: hyperthermia; LPS: lipopolysaccharide.