Figure 1.

Effects of HRS on the expression of Beclin-1 and LC3II/I in LPS-induced ALI in mice. The mice were administrated intratracheal LPS (10 mg/kg, dissolved in saline; 50 μL/per mouse) or an equal volume of saline (Saline (I.T.)) to induce ALI. HRS (10 mL/kg) or an equal volume of saline was administrated intraperitoneally 1 h before LPS treatment. Twelve hours later, the mice were sacrificed and samples were collected. Data are represented as mean ± SD of three independent experiments. **P < 0.01 vs. Con group, ^##P < 0.01 vs. LPS group. HRS: hydrogen- rich saline; Con: control; LPS: lipopolysaccharide.