Figure 2.

BALF and lung homogenate levels of IL-5 and IL-13 induced by mIL-25 challenge. Mice were intranasal injected with mIL-25 or saline and were sacrificed at days 3, 7, 19, and 31 for BALF and lung homogenate collection. ELISA was used to detect the BALF and lung homogenate levels of IL-5 (a and b) and IL-13 (c and d). Data are means ± SEMs (N = 5 per group) (mIL-25 vs. saline group at indicated time points, *P < .05, **P < .01, ***P < .001 calculated by two-way ANOVA with Bonferroni post hoc test). IL-25: interleukin 25; IL-5: interleukin 5; IL-13: interleukin 13; BALF: bronchoalveolar lavage fluid; NS: normal saline. (A color version of this figure is available in the online journal.)