Table 3.
Sequence, parent gene and structural position of 13 PvMSP-7 peptides that gave significant responses on the peptide microarray in all age groups, compared to the negative control
| Epitope sequence | PvMSP7 paralog | Position within protein sequence (aa) | Signal intensity | paadj | |
|---|---|---|---|---|---|
| Infecteda | Naive | ||||
| CLLLLCAGPVLGDDD | A | 10–25 | 10.0182341 | 6.403 | 0.003 |
| EAVQWGPATEEVVAE | A | 158–173 | 10.9368279 | 7.083 | 0.002 |
| KLLDTMLTNGQVERE | A | 298–313 | 9.47392489 | 6.693 | 0.009 |
| TMLTNGQVEREKKNT | A | 302–317 | 9.09588506 | 5.900 | 0.014 |
| EREKKNTLIKTFKKA | A | 310–325 | 8.31646604 | 4.383 | 0.004 |
| KNTLIKTFKKALYDK | A | 314–329 | 5.52137066 | 0.000 | 0.012 |
| YESIHGEDEPQVVPS | B | 178–193 | 8.86022031 | 5.274 | 0.009 |
| EEESLGHLLESEDAD | H | 83–98 | 9.86610447 | 6.932 | 0.011 |
| DEIHVPPFHSKYNDF | I | 272–287 | 9.52211097 | 7.151 | 0.016 |
| EDTTPKEQQEDQNVS | L | 91–106 | 8.74109552 | 5.510 | 0.012 |
| QEENTQVKNVIFTEK | L | 123–138 | 9.29166832 | 4.963 | 0.010 |
| EAVDEEAEKEDTAVI | L | 139–154 | 11.8856457 | 7.626 | 0.002 |
| SSAESAPNEPDVNTT | L | 207–222 | 10.2973557 | 8.476 | 0.026 |
aMean value across all age groups