Table 2.
The results of leucocyte, NLR, CRP and platelet/MPV based on the percentage of eosinophils (<4% and ≥4%) and in subgroups based on the presence and absence of lower respiratory tract infections in paediatric patients (n = 991) with asthma.
| Eosinophil<4% | Eosinophil≥4% | Statistical significancea | Eosinophil <4%Infection (–)n = 507 | Eosinophil ≥4%Infection (–)n = 269 | Eosinophil <4%Infection (+)n = 158 | Eosinophil ≥4%Infection (+)n = 57 | Statistical significanceb | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Leucocyte, ×109/l | 665 | 8.94 (7.18–11.20) | 326 | 8.58 (7.00–10.21) | P = 0.07 | 8.59 (6.90–10.65) | 8.48 (6.98–10.09) | 9.77 (7.84–12.52) | 8.96 (7.10–11.11) | P = 0.003 |
| NLR | 665 | 1.79 (1.21–2.93) | 326 | 1.36 (0.99–1.89) | P < 0.001 | 1.68 (1.16–2.72) | 1.32 (0.98–1.76) | 2.15 (1.15–3.44) | 1.69 (1.08–2.41) | P < 0.001 |
| CRP, mg/l | 447 | 3.9 (3.3–15.6) | 207 | 3.3 (3.3–9.1) | P = 0.001 | 3.3 (3.3–10.3) | 3.3 (3.3–7.1) | 9.5 (3.3–33.2) | 5.0 (3.3–15.4) | P = 0.001 |
| Platelet/MPV | 273 | 38.62 (30.37–47.20) | 107 | 38.46 (32.46–44.65) | NS | 37.42 (29.88–46.61) | 38.47 (32.09–46.33) | 39.03 (32.55–48.41) | 38.29 (33.98–40.54) | NS |
Data presented as n of patients and median (interquartile range).
NLR, neutrophil-to-lymphocyte ratio; CRP, C-reactive protein; MPV, mean platelet volume; NS, no significant between-group difference (P ≥0.05).
aMann–Whitney U-test; bKruskal–Wallis test.