Table 1.
Six differentially methylated sites identified in six samples of sinonasal inverted papilloma (SNIP) and five samples of sinonasal squamous cell carcinoma arising in SNIPs.
| Target identification | Differential scorea | UCSC reference gene name | UCSC reference gene location | Island name | C-phosphate-G | Adjusted P-values |
|---|---|---|---|---|---|---|
| cg03537810 | 21.9 | PLEC | Body | chr8:145018815-145019214 | N_Shore | P = 0.006418433 |
| cg04018533 | 22.6 | PLEC; MIR661 | Body | chr8:145017868-145018444 | S_Shore | P = 0.005434417 |
| cg09235308 | 20.8 | PLEC; MIR661 | Body | chr8:145017868-145018444 | S_Shore | P = 0.008295069 |
| cg10451724 | 21.9 | PLEC; MIR661 | Body | chr8:145017868-145018444 | S_Shore | P = 0.005418433 |
| cg11956819 | 21.9 | PLEC | Body | chr8:145018815-145019214 | Island | P = 0.006418433 |
| cg27391679 | 20.4 | OPA3 | Body | chr19:46056783-46057149 | Island | P = 0.009097289 |
a
A differential score equal to 20, 30 or 40 corresponds to a significant P-value of 0.01, 0.001 or 0.0001, respectively.
UCSC, University of California, Santa Cruz; PLEC, plectin; MIR661, microRNA 661; OPA3, outer mitochondrial membrane lipid metabolism regulator.