Table 2.
Characteristic | Univariate |
Multivariate |
||||
---|---|---|---|---|---|---|
n | 5-year OS rate (%) | p-value | HR | 95% CI | p-value | |
Age (years) | 0.82 | |||||
≥60 | 163 | 67.2 | ||||
<60 | 200 | 72.1 | ||||
Sex | 0.12 | |||||
Male | 221 | 72.5 | ||||
Female | 142 | 71.7 | ||||
Tumor site | 0.37 | |||||
Colon | 137 | 70.4 | ||||
Rectum | 226 | 69.6 | ||||
Tumor size (cm) | 0.16 | |||||
≥5 | 136 | 69.3 | ||||
<5 | 227 | 72.8 | ||||
Tumor invasion depth | 0.02 | |||||
T1 + T2 | 191 | 75.3 | ||||
T3 + T4 | 172 | 69.2 | ||||
Lymph node involvement | 0.01 | |||||
N0 | 149 | 74.2 | ||||
N1 | 214 | 67.6 | ||||
Clinical stage (TNM) | 0.04 | 3.32 | 1.98–8.62 | <0.01 | ||
I + II | 160 | 75.3 | ||||
III | 213 | 6412 | ||||
Pathological differentiation | 0.01 | 1.27 | 1.02–3.67 | 0.01 | ||
Good/moderate | 218 | 75.1 | ||||
Poor | 145 | 64.2 | ||||
Serum miR-142-3p | 0.03 | 2.68 | 1.21–7.95 | <0.01 | ||
Low | 236 | 67.4 | ||||
High | 127 | 76.9 |
OS, overall survival; HR, hazard ratio; CI, confidence interval; miR-142-3p, microRNA-142-3p.