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PET imaging with 89Zr-DFO-9E7.4 in the subcutaneous (SC) model. Maximum intensity projections of PET imaging at 24 h post-injection (PI) (A;D), 48 h PI (B;E) and 72 h PI (C;F) showing uptake of a subcutaneous tumor and of an inguinal lymph node (Tumors are indicated by red arrows) (Mouse 8). Green arrows showed conspicuous binding of free 89Zr over time at sites of osseous turnover.
