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. 2019 May 24;20(10):2564. doi: 10.3390/ijms20102564

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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PET imaging with ⁶⁴Cu-TE2A-9E7.4 and ⁸⁹Zr-DFO-9E7.4. Bioluminescence imaging (A) revealing lesions in the spine and the left iliac wing. Maximum intensity projections of ¹⁸F-FDG-PET and CT (B;C) and maximum intensity projections of PET and CT imaging with ⁶⁴Cu-TE2A-9E7.4 at 24 h post-injection (PI) (D;E), realized 33 days post multiple myeloma (MM) cells injection in Mouse 18. Maximum intensity projections of ¹⁸F-FDG-PET and CT (F;G) and maximum intensity projections of PET and CT imaging with ⁸⁹Zr-DFO-9E7.4 at 24 h (PI) (H;I), realized 40 days post MM cells injection. Pathological uptakes were spotted by red arrows in the skull, spine and the left iliac wing.