Table 1.

Biodistribution results and organ-to-blood ratios of ⁸⁹Zr-DFO-9E7.4, ⁸⁹Zr-oxalate in tumor-bearing mice. Ex vivo biodistribution results and organ-to-blood ratios of ⁸⁹Zr-DFO-9E7.4 at 24 h and 72 h post-injection (PI), in the subcutaneous tumor model (n = 3 for each group). Ex vivo biodistribution results and organ-to-blood ratios of ⁸⁹Zr-oxalate at 24 h PI (n = 3). Values are expressed in percentage of the injected radioactive dose per gram of tissue (%ID/g) and presented as mean +/- SD.

Organs	89Zr-DFO-9E7.4 (24 h PI)		89Zr-DFO-9E7.4 (24 h PI)		89Zr-DFO-9E7.4 (72 h PI)		89Zr-DFO-9E7.4 (72 h PI)		89Zr-Oxalate (24 h PI)		89Zr-Oxalate (24 h PI)
			Ratio Organs/Blood				Ratio Organs/Blood				Ratio Organs/Blood
	Median	SD	Median	SD	Median	SD	Median	SD	Median	SD	Median	SD
Tumor	12.48	4.77	1.42	0.47	4.53	1.76	3.42	0.22	9.67	2.52	0.83	0.15
Blood	5.33	0.95	1.00	0.00	1.77	0.85	1.00	0.00	11.57	1.38	1.00	0.00
Liver	13.93	1.36	2.30	1.00	9.90	1.75	6.44	2.55	8.60	0.53	0.75	0.13
Kidney	5.78	2.83	0.62	0.13	3.60	1.37	2.15	0.61	12.33	1.53	1.09	0.27
Gut	7.03	0.95	1.34	0.41	6.13	2.47	3.65	0.98	5.47	1.29	0.47	0.06
Lungs	5.70	2.79	0.86	0.22	2.77	1.14	1.60	0.16	7.90	0.79	0.69	0.01
Muscle	1.05	0.49	0.11	0.03	0.27	0.15	0.16	0.04	2.63	0.21	0.23	0.01
Spleen	10.78	1.86	2.00	0.56	7.23	1.01	4.85	2.36	10.90	1.01	0.96	0.21
Skin	3.28	0.90	0.41	0.25	1.40	0.69	0.80	0.18	3.77	0.15	0.33	0.05
Brain	0.68	0.71	0.05	0.03	0.20	0.17	0.20	0.25	0.50	0.10	0.04	0.01
Heart	4.60	2.81	0.45	0.02	0.93	0.64	0.46	0.29	8.70	1.13	0.77	0.20
Flat Bone	2.98	1.07	0.34	0.12	3.43	1.12	2.11	0.60	39.20	2.03	3.44	0.58
Femur	3.23	1.38	0.45	0.11	3.30	0.70	2.16	0.63	38.43	1.40	3.37	0.55
Stomach	5.30	1.35	0.62	0.46	2.77	0.45	1.82	0.76	14.67	1.53	1.29	0.28