Skip to main content
. 2019 Apr 14;597(10):2691–2705. doi: 10.1113/JP277241

Figure 8. Models to explain single low Po gating vs. multiple high Po gating modes of TRIC‐B.

Figure 8

A, model illustrating how the simultaneous opening of none, one, two and three pores within a single trimeric TRIC‐B channel could give rise to the known gating characteristics of a single SR K+‐channel. B, the model suggests how multiple TRIC‐B channels, by physically interacting, could switch to a high Po mode, resulting in an increase of simultaneous openings of multiple pores within each trimeric TRIC‐B channel. [Color figure can be viewed at wileyonlinelibrary.com]