Table 5.
Epitope specificity of anti-factor H (FH) antibodies to short consensus repeats (SCR) of FH.
| References | SCR 1–4 | SCR 1–7 | SCR 7 | SCR 5–8 | SCR 8–14 | SCR 9–12 | SCR 11–14 | SCR 13–16 | SCR 15–20 | SCR 17–20 | SCR 19–20 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Blanc et al. (13) | 13/14 | 17/18 | 5/18 | 18/18 | 8/17 | ||||||
| Bhattacharjee et al. (38) | 10/10 | 10/10 | |||||||||
| Moore et al. (39) | 1/12 | 7/12 | |||||||||
| Jozsi et al. (11) | 0/5 | 1/5 | 5/5 | 5/5 | |||||||
| Jozsi et al. (5) | 0/16 | 4/16 | 16/16 | 16/16 | |||||||
| Nozal et al. (14) | 1/14 | 1/14 | 2/17 | 12/14 | |||||||
| Guo et al. (40) | 4/36 | 6/36 | 4/36 | 12/36 | |||||||
| Gurjar et al. (16) | 21/21 | 21/21 | |||||||||
| Brocklebank et al. (25) | 5/17 | 1/17# | 1/17* | 15/17 | |||||||
| Present study | 3/8 | 4/8 | 7/8 | 7/8 | 8/8 | ||||||
| Total (%) | |||||||||||
| N-terminal of FH | Mid-portion of FH | C-terminal of FH | |||||||||
Short consensus repeats (SCR) 8–15;
SCR 16–18.