Figure 2.
(A) Construction of metallo-nanodrugs through multicomponent (small peptides, photosensitizers, zinc ions) coordination self-assembly. (B) SEM image of the metallo-nanodrugs Fmoc-H/Zn2+/Ce6. (C) Size and PDI of metallo-nanodrug under conditions mimicking physiological circulation. (D) Schematic illustration of ultrasensitive responsiveness to pH and GSH change. (E) Fluorescence images showing the preferential accumulation of metallo-nanodrugs at tumor sites in contrast to unencapsulated photosensitizers. (F) Tumor growth profiles after PDT. Adapted with permission from Ref 26. Copyright 2018 American Chemical Society.