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The precise inclusion of single-stranded DNA using isoreticular MOFs: (A) the ssDNA transfection procedure of ssDNA@Ni-IRMOF-74-II; (B) the protection studies of ssDNA using different porous nanostructures in FBS; (C) the intracellular delivery of ssDNA using ssDNA@Ni-IRMOF-74-II and pure ssDNA; (D) gene silencing efficiency of MCF-7 cells for the DNAzyme delivery with Ni-IRMOF-74-II, Lipo, and Neofec 172. Copyright 2018 Nature.
