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. Author manuscript; available in PMC: 2020 Jan 23.
Published in final edited form as: Chem Rev. 2018 Nov 26;119(2):1193–1220. doi: 10.1021/acs.chemrev.8b00285

Figure 16.

Figure 16

Top panels are ribbon diagrams of the PBPs. The bottom panels are close-ups of the substrate binding sites. Siderophores are shown in white stick and active site Tyr and Arg residues are indicated. A. Mtb FecB2 (PDB: 4PM4; blue), B. S. aureus heme:IsdE complex (PDB:2Q8Q; pink), and C. P. aeruginosa heme:PhuT complex (PDB:2R79; orange).