Skip to main content
. Author manuscript; available in PMC: 2019 Jun 14.
Published in final edited form as: Nat Genet. 2018 Jun 11;50(7):928–936. doi: 10.1038/s41588-018-0142-8

Table 2 |.

Estimation of polygenic risk scores by using 147 prostate cancer-susceptibility variants

Risk category percentilea Relative risk 95% CI
<1 0.15 0.11–0.20
1–10 0.35 0.32–0.37
10–25 0.54 0.51–0.57
25–75 1.00 (baseline)
75–90 1.74 1.67–1.82
90–99 2.69 2.55–2.82
≥99 5.71 5.04–6.48
a

PRS percentiles based on the cumulative score distributed among controls. The beta coefficients computed from the European overall meta-analysis were applied to determine the PRS risk among individuals in the OncoArray study.