Figure 2.

(a) After oral administration, MPBZs target the inflamed colon from the epithelium via mechanisms mediated by size and charge. (b) Fluorescence imaging of colons from control mice and mice with DSS-induced colitis after oral FITC-labelled MPBZ treatment. (c) Biodistribution images and (d) corresponding fluorescence intensity values in the colons of mice treated with MPBZs were carried out after oral administration of 2 h and 6 h. Scale bar: 400 μm. (e) Biodistribution images and (f) corresponding fluorescence intensity values in the organs of mice treated with MPBZs were measured at various time points after oral administration.