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. Author manuscript; available in PMC: 2019 Jun 14.
Published in final edited form as: Nat Methods. 2019 Apr 29;16(5):369–379. doi: 10.1038/s41592-019-0395-x

Figure 8: Dynamics probed in response to radiation damage.

Figure 8:

When less than 1 e−/Å2 (left) was used for structure determination of Proteinase K (1.7Å, PDB ID: 6CL7), local radiation damage was minimal. When higher doses (right) were used (2.8Å, PDB ID: 6CLA) the damaging effects of the beam can already be seen with the breakage of disulfide bonds and the lower attainable resolution. Density maps (2Fo-Fc) in gray are contoured at 1.5σ.