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. Author manuscript; available in PMC: 2019 Jun 14.
Published in final edited form as: Annu Rev Biomed Eng. 2018 Jun 4;20:301–327. doi: 10.1146/annurev-bioeng-071516-044532

Figure 8.

Figure 8.

A similar experiment conducted with STS rather than anesthesia. Equivalent core temperature was calculated as the weighted average of actual core (80%) and mean skin (20%) temperatures (151; 152) during cooling from a thermoneutral state of full AVA vasoconstriction achieved by adjusting circulating water temperature in a full body suit. Mean skin temperature was dropped by reducing temperature of water circulated through the suit. STS was applied continuously starting at the thermoneutral state, achieving a higher GSBF prior to cooling. STS reduced the vasoconstriction threshold temperature by about 0.5°C, but increased the gain by a little over 2.