Table 1.

Differentially expressed microRNAs between SCD patients on HU and off HU in cross-sectional analysis.

microRNA-ID Fold-change q-value (%) p-values
microRNA	microRNA-ID Fold-change	q-values	p-values
hsa-miR-105-5p	1.566	35.526	0.01644
hsa-miR-188-3p	1.525	35.526	0.01737
hsa-miR-561-3p	1.451	35.526	0.01757
hsa-miR-3074-3p	1.509	35.526	0.01871
hsa-miR-892a	1.327	35.526	0.02010
hsa-miR-490-5p	1.532	35.526	0.02534
hsa-miR-1258	1.339	35.526	0.02519
hsa-miR-629-5p	1.183	35.526	0.02802

In order to avoid possible residual effect of previous HU exposure Patient GS01 was remove from this analysis for non-compliance at initial administration of HU that he stopped for 3 months, before resuming treatment to achieve MTD.