Table 1.
Means and standard deviations (in parentheses) for participant characteristics of caregivers and patients with neurodegenerative disease (or partners and controls) by diagnosis group, unless otherwise noted
| Characteristic | AD | bvFTD | CBS | HCs | nfvPPA | PSP | svPPA |
|---|---|---|---|---|---|---|---|
| Subjects, n | 35 | 32 | 17 | 23 | 15 | 17 | 23 |
| Caregiver/partner sex, % female | 71 | 59 | 53 | 48 | 53 | 53 | 48 |
| Caregiver/partner age, years | 59.19 (8.35) | 58.56 (14.39) | 60.65 (11.09) | 64.60 (10.66) | 68.25 (15.73) | 62.94 (8.00) | 66.38 (14.80) |
| Caregiver/partner relationship, % spouses | 86 | 81 | 71 | 83 | 93 | 88 | 83 |
| Caregiver/partner ethnicity, n | |||||||
| White/Caucasian/European American | 31 | 24 | 12 | 22 | 14 | 16 | 23 |
| Latino/Chicano/Hispanic | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
| Black/Black American/Afro-Caribbean | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
| Asian/Asian American/South Asian | 0 | 3 | 2 | 1 | 1 | 1 | 1 |
| Multi-racial/other | 4 | 4 | 1 | 0 | 0 | 0 | 0 |
| Patient Neuropsychiatric Inventory (NPI) score | 21.03 (24.22) | 41.45 (18.20) | 22.40 (23.31) | −(−) | 15.14(13.20) | 33.53 (19.30) | 36.13 (19.12) |
| Patient Clinical Dementia Rating (CDR-Box) score | 3.99 (1.88) | 6.84 (3.39) | 3.82 (2.49) | 0.00 (0.00) | 2.20 (2.33) | 5.82 (2.70) | 3.95 (2.65) |
| Patient Mini-Mental State Examination (MMSE) score | 22.23 (4.81) | 23.31 (5.51) | 22.18 (6.49) | 29.60 (0.58) | 23.40 (7.71) | 26.70 (3.12) | 23.36 (5.48) |
| Caregiver/partner Symptom Checklist 90 (SCL-90) score | 0.33 (0.23) | 0.53 (0.36) | 0.59 (0.74) | 0.24 (0.20) | 0.56 (0.44) | 0.28 (0.18) | 0.30 (0.33) |
| Caregiver/partner Short Form Health Survey (SF-36) score | 78.97 (11.82) | 75.51 (12.00) | 73.88 (19.48) | 85.20 (8.41) | 72.10 (18.16) | 77.39 (19.56) | 80.81 (11.92) |
NPI, patient neuropsychiatric (e.g., behavioral) symptoms; CDR-Box, dementia severity; MMSE, cognitive functioning; SCL-90, severity of psychopathological symptoms; SF-36, global health outcomes; AD, Alzheimer’s disease; bvFTD, behavioral-variant frontotemporal dementia; CBS, corticobasal syndrome; HCs, healthy controls; nfvPPA, nonfluent-variant primary progressive aphasia; PSP, progressive supranuclear palsy; svPPA, semantic-variant primary progressive aphasia.