Fig. 6. Inflammatory gene expression at the maternal-fetal interface and myometrium prior to preterm birth.
Decidual and myometrial tissues from dams injected with αCD3ε (or isotype control), LPS (or PBS control), or RU486 (or DMSO control). Heat map visualization of inflammatory and contractility-related gene expression in the (A) decidual and (B) myometrial tissues. (C&D) Messenger (m)RNA expression of selected genes in decidual and myometrial tissues. Negative (−)∆Ct values were calculated using Actb, Gusb, Gapdh and Hsp90ab1 as reference genes. Data are from individual dams (n=7-16 each). The p-values were determined by unpaired 2-tailed t-test. Data are shown as scatter plots (median).
