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. Author manuscript; available in PMC: 2020 May 2.
Published in final edited form as: Chembiochem. 2019 Mar 14;20(9):1133–1138. doi: 10.1002/cbic.201800756

Figure 4.

Figure 4.

Inhibition of KDM4A and its mutants by NOG analogues. (A) Heat-map diagram of % inhibition of demethylase activity by 100 μM of NOG and its analogues as determined by MALDI-MS. (B-C) IC50 of ethyl-NOG 3 and propyl-NOG 5 towards N198A mutant.