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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Cell Biochem. 2019 Apr 8;120(8):14065–14075. doi: 10.1002/jcb.28682

Figure 2.

Figure 2.

Results of interactions of ligands DAST, FB-28, and FB-71 with 19S-associated DUBs UCHL5 and USP14 through computational molecular docking. Docking studies were conducted between receptors UCHL5 (A-C) and USP14 (D-F) with ligands DAST, FB-28, and FB-71 (left, middle, and right columns, respectively, labeled above). The outputted predictions of the conformations (docking states) between known amino acid residues of known active sites of USP14 and UCHL5 and the ligands (Optical Brighteners) are displayed. DAST, 4,4’-Diamino-2,2’-stilbenedisulfonic acid; DUB, deubiquitinating enzyme; FB-28, Fluorescent Brightener 28; FB-71, Fluorescent Brightener 71.