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Cleavage and polyadenylation: Cap binding complex (CBC) binds 5′ guanosine cap. Cleavage factor 1A (CF1A) is recruited to Ser2 phosphorylated CTD of RNAPII. Cleavage and polyadenylation factor (CPF) is recruited and cleaves RNA after polyadenylation signal. Poly(A) polymerase polyadenylates 3′ end of RNA following cleavage. Xrn2 degrades 5′ end of uncapped RNA and removes RNAPII from the DNA template
