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Nrd1‐Nab3‐Sen1 termination: Nrd1 is recruited to the site of transcription by Ser5 phosphorylated CTD. Nab3 and Nrd1 form a heterodimer and bind to RNA via their RNA recognition motif domains. Nab3 and Nrd1 are thought to be able to recruit Sen1, which then catches RNAPII and unwinds the DNA/RNA hybrid (also known as R‐loop). TRAMP unwinds RNA and its subunit Trf4 polyadenylates the 3′ end of RNA for processing and/or degradation. The exosome complex then degrades the RNA 3′–5′
